![]() ![]() The objective of resting state experiments is to capture the statistical properties of endogenously generated (synonyms: spontaneous intrinsic) neural activity. ![]() The operational definition of “rest” may be generalized to encompass engagement in a controlled task as long as all imposed temporal structure is randomly phased with respect to the fMRI acquisition e.g., ( Fransson, 2006). The eyes may be closed or open, with or without visual fixation. In the context of experimentation, “rest” is an operational definition referring to a constant condition without imposed stimuli or other behaviorally salient events. Given the apparently contradictory characterization of “rest” (see above) it is prudent to begin with a definition. We then briefly review the history of resting state fMRI studies performed our laboratory. Below we present a brief account of scientific milestones that have shaped our view of the resting state. An expanded view of the tension between task-based and resting-state modes of investigation has been outlined in a recent review ( Raichle, 2009). However, scientific investigation of the brain’s “resting state” presents conceptual as well as methodological challenges whereas studying the brain’s responses to controlled stimuli, that is, the experimental paradigm that has dominated systems neuroscience throughout the latter half of the 20 th century, is comparatively straightforward. Rest is… far from restful” ( Seneca, 1969). As noted by Seneca in ~60 A.D., “The fact that the body is lying down is no reason for supposing that the mind is at peace. Whether or not you store this new entity in a database or in application memory (like a traditional Session object) is up to you, but, either way, the new object is less about "state" on the server and more about creating a new entity for the user to interact with.It has been appreciated for at least two millennia that the brains of humans exhibit ongoing activity regardless of the presence or absence of any observable behaviors. If you are, on the other hand, trying to manage some sort of new object on the server-such as a shopping cart-then the REST answer is that you are actually creating a new entity that can be accessed like any other by a direct URL. This is an implementation of Martin Fowler's "Client State" design pattern (detailed in full in his book, Patterns of Enterprise Application Architecture see here for a reference). If you are truly trying to manage request-based state (such as when a user is working through a multi-screen wizard or some other navigation-based workflow), then the REST answer is that state should be sent back-and-forth with each request/response (using something like a hidden text field, a query string, or POST data stored in a form). ![]() There are 2 REST answers to this, depending on what specifically you are trying to do. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |